Written by Alexander Kalisch, Markus Horneber and the CAM-Cancer Consortium.
Updated February 8, 2017

Fermented wheat germ extract

Does it work ?

Eight controlled clinical trials in adults were carried out with patients diagnosed with head and neck cancer, malignant melanoma, and colorectal carcinoma and in children with diverse malignancies;3 4 5 6 17 18 19 they are described in Table 1. All trials reported benefits of FWGE treatment: two studies found longer overall and progression-free survival times,4 5 two studies identified reduced relapse rates,3 5 three trials showed improved quality of life6 17 19 and another study found reduced incidence of febrile neutropenia.18 However, the evidence that treatment with FWGE confers benefits to cancer patients is very weak, as all study data were at high risk of bias: only one study was a randomized clinical trial and all studies were open labelled, had small sample sizes, and poor reporting quality. All trials used the same patented FWGE from one manufacturer.

Citation Alexander Kalisch, Markus Horneber, CAM-Cancer Consortium. Fermented wheat germ extract [online document]. http://ws.cam-cancer.org/The-Summaries/Dietary-approaches/Fermented-wheat-germ-extract. February 8, 2017.


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